Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study.

@article{Thior2006BreastfeedingPI,
  title={Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study.},
  author={I. Thior and S. Lockman and L. Smeaton and R. Shapiro and C. Wester and S. J. Heymann and P. Gilbert and L. Stevens and T. Peter and S. Kim and E. van Widenfelt and C. Moffat and P. Ndase and Peter Arimi and P. Kebaabetswe and P. Mazonde and J. Makhema and K. Mcintosh and V. Novitsky and T. Lee and R. Marlink and S. Lagakos and M. Essex},
  journal={JAMA},
  year={2006},
  volume={296 7},
  pages={
          794-805
        }
}
CONTEXT Postnatal transmission of human immunodeficiency virus-1 (HIV) via breastfeeding reverses gains achieved by perinatal antiretroviral interventions. OBJECTIVE To compare the efficacy and safety of 2 infant feeding strategies for the prevention of postnatal mother-to-child HIV transmission. DESIGN, SETTING, AND PATIENTS A 2 x 2 factorial randomized clinical trial with peripartum (single-dose nevirapine vs placebo) and postpartum infant feeding (formula vs breastfeeding with infant… Expand
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Paper Mentions

Interventional Clinical Trial
The purpose of this study is to find the most effective and safe treatment to prevent the passage of HIV from an infected mother to her baby.  
ConditionsHIV Infection, Infant Risk for HIV Infection by MTCT
InterventionDrug
Prolonged breastfeeding and HIV transmission.
  • Highly Influenced
Prevention of Mother-to-Child Transmission of HIV-1 Through Breast-Feeding by Treating Infants Prophylactically With Lamivudine in Dar es Salaam, Tanzania: The Mitra Study
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