Breast size and breast cancer: a systematic review.

  title={Breast size and breast cancer: a systematic review.},
  author={Leigh A. Jansen and Robert Backstein and M. H. Brown},
  journal={Journal of plastic, reconstructive \& aesthetic surgery : JPRAS},
  volume={67 12},

Introduction to Breast Carcinogenesis – Symptoms, Risks factors, Treatment and Management

A model was developed and presented to encapsulate the knowledge of the benefits associated with exercise on breast cancer outcomes through adiposity and immunological mechanisms to help in the decreased of mortality rate in woman and men who has and are likely to test malignancy to breast cancer disease.

Breast cancer in young women Aspects of heredity and contralateral disease

Both young age and the identification of a pathogenic variant are associated with an increased risk for the development of a new primary breast cancer among women who have previously been diagnosed with breast cancer.

The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis

No evidence of a relationship between genetically predicted breast size and breast cancer risk was found except when using the weighted median and weighted mode methods, and only with oestrogen receptor (ER)-negative risk.

Cancer Progress and Priorities: Breast Cancer

Survival has increased over the past few decades, with the introduction of screening mammography and improved treatments, however, progress has not been seen equally among all ethnicities/races or with all breast cancer subtypes (e.g., triple negative).

Breast Volume Asymmetry Value, Ratio, and Cancer Risk

There is a positive correlation between breast asymmetry ratio over 20% and breast cancer risk and these results need to be confirmed by prospective randomized controlled trials.


Despite major sequelae such as external permanent scarring and decrease in breastfeeding and nipple sensation, breast reduction surgery is the operation that records the highest patient satisfaction in plastic, reconstructive and aesthetica surgery, as it provides physical and psychological relief by eliminating the heavy weight that affects the shoulders, back and neck.

The tumor-to-breast volume ratio (TBR) predicts cancer-specific survival in breast cancer patients who underwent modified radical mastectomy

The tumor-to-breast volume ratio (TBR) was evaluated to evaluate the relative tumor size and determined the prognostic impact of TBR on survival in patients with breast cancer and revealed that high TBR was independently associated with poor prognosis in breast cancer patients.

A propensity score–matched analysis of breast-conserving surgery plus whole-breast irradiation versus mastectomy in breast cancer

Patients with HER2 subtype BC (T1-2, N0-3) who underwent BCS’+ WBI or mastectomy without external radiotherapy for a first primary BC had a statistically significantly higher risk of IBTR than patients who underwent mastectomy, however, survival was not statistically significantly different between the groups.

Breast density measured volumetrically in a clinical environment: cross-sectional study with photon counting technology

BDen diminishes with age in women with or without BC, but it is generally higher in Women with BC, and GVol could be a more robust indicator associated with BC risk than BDen.


It is stated that insufficient knowledge of females about breast cancer, mammography and deficit knowledge on the practice of Breast self examination among south Indian women population is stated.



A prospective study of breast size and premenopausal breast cancer incidence

Larger bra cup size at a young age is associated with a higher incidence of premenopausal breast cancer, though this association is limited to leaner women, while there was no significant association among women with a BMI of 25 kg/m2 or higher.

Is breast size a predictor of breast cancer risk or the laterality of the tumor?

Breast size was associated with cancer of the left breast but not the right, and size differences were small since the area of the larger breast was less than 10 percent greater than the smaller breast among half of the case subjects.

Breast size and breast cancer risk

Based on a large number of caucasian women, this study provides conclusive evidence of a lack of appreciable association between breast size and breast cancer risk in this Italian population.

Breast augmentation: a risk factor for breast cancer?

Women who undergo breast augmentation with silicone implants have a lower risk of breast cancer than the general population, and this finding suggests that these women are drawn from a population already at low risk and that the implants do not substantially increase the risk.

Breast cancer detection and survival among women with cosmetic breast implants: systematic review and meta-analysis of observational studies

It is suggested that cosmetic breast augmentation adversely affects the survival of women who are subsequently diagnosed as having breast cancer, and some studies included in the meta-analysis on survival should be interpreted with caution.

Breast size and mammographic pattern in relation to breast cancer risk.

In Swedish women, and perhaps in Caucasian women in general, small breast size is associated with increasing breast risk through its association with high- risk parenchymal pattern, in contrast to the fact that Asian women, who in general have breasts of smaller size, have low prevalence of high-risk paren chymal patterns as well as low rates of breast cancer.

Breast Reduction Surgery and Breast Cancer Risk: Does Reduction Mammaplasty Have a Role in Primary Prevention Strategies for Women at High Risk of Breast Cancer?

The availability of a more acceptable surgical option for primary prevention of breast cancer could increase the number of women willing to choose risk reduction surgery and thus may result in an overall reduction in breast cancer mortality among high-risk women.

Breast Enlargement and Reduction: Results from a Breast Cancer Case‐Control Study

The results confirm several record linkage studies but contradict some clinical studies that suggest an adverse effect, and additional investigations are needed in relation to specific types of breast implants, including the polyurethane‐coated implants, which have been linked to high cancer rates in laboratory animals.

Cancer following breast reduction surgery in Denmark

The findings indicate that breast reduction surgery among women over age 40 is associated with a lowerssequent risk of breast cancer, but the surgery and presumably glandularmass appear less closely related to breast cancer risk among youngerwomen.