Breast screening with ultrasound in women with mammography-negative dense breasts: evidence on incremental cancer detection and false positives, and associated cost.

@article{Corsetti2008BreastSW,
  title={Breast screening with ultrasound in women with mammography-negative dense breasts: evidence on incremental cancer detection and false positives, and associated cost.},
  author={Vittorio Corsetti and Nehmat Houssami and Aurora Ferrari and Marco Ghirardi and Sergio Bellarosa and Osvaldo Angelini and Claudio Bani and Pasquale Sardo and Giuseppe Remida and Enzo Galligioni and Stefano Ciatto},
  journal={European journal of cancer},
  year={2008},
  volume={44 4},
  pages={539-44}
}
BACKGROUND We evaluated the contribution of ultrasound (US) in detecting breast cancer in women with dense breasts and negative mammograms. METHODS 9157 (35.8%) of 25,572 self-referring women during 2000-2007 had BI-RADS D3-4 negative mammograms - all were screened with bilateral US. RESULTS US detected 37 cancers - incremental cancer detection rate (ICDR) was 0.40% (95% CI: 0.39-0.41%); ICDR was 0.33% in women <50 and 0.51% in those 50 years and older. US detected a larger proportion of… CONTINUE READING

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