Corpus ID: 21771227

Breast implant (PIP), chronic inflammation and cancer: is there a connection? Case report.

  title={Breast implant (PIP), chronic inflammation and cancer: is there a connection? Case report.},
  author={A. Gubitosi and Giovanni Docimo and Roberto Ruggiero and Alessandro Esposito and Emanuela Esposito and Fabrizio Foroni},
  journal={Annali italiani di chirurgia},
The "PIP problem", in the field of the breast augmentation, represents today a surgical epidemiological emergency. The massive media coverage produced a kind of mass fear and many women are asking for explantations. A 47 y.o. female, breasts implanted with PIP devices for breast augmentation in 1998, came to our clinic asking for explantation and excisional biopsy of a 2.5 cm nodule adjacent to the upper side of the breast implant capsule. The outcome of the pathologic examination of the… Expand
Recall management of patients with Rofil Medical breast implants.
The quality of the explanted Rofil implants was comparable to PIP implants, with a higher rupture prevalence compared with other, non-affected implants, Nevertheless, the acceptance of breast implants for reimplantation remained high. Expand


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A series of cases where carcinoma and carcinoma in situ of the breast within or mmediately adjacent to the implant capsule are reported are reported, suggesting that its ascular nature may predispose tumor seeding to the capsule at rates higher than previously believed. Expand
Postmastectomy Reconstruction of the Previously Augmented Breast: Diagnosis, Staging, Methodology, and Outcome
A retrospective review of the senior author's reconstructive practice was performed, revealing 21 women who underwent postmastectomy breast reconstruction after previous breast augmentation, and cosmetic results were generally good‐to‐excellent, comparable to or better than those in the matched controls. Expand
The PIP mammary prosthesis: a product recall study.
  • M. Berry, J. Stanek
  • Medicine
  • Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • 2012
This cohort correlates reduced implant longevity with each successive year from 2000 and no cases of ALCL have been diagnosed, but the overall patient rupture rate for the PIP implant is 15.9-33.8%. Expand
Immediate Breast Reconstruction in the Previously Augmented Patient
Patients with previous augmentation mammoplasty are more likely to undergo implant-based reconstruction compared with nonaugmented women and the presence of implants does not delay the detection of breast cancer when compared with a control group of patients who do not have breast implants. Expand
Does Immediate Breast Reconstruction after Mastectomy affect the Initiation of Adjuvant Chemotherapy?
IBR delays the initiation of chemotherapy, but does not lead to omission or significant clinical delay in chemotherapy, and the type of reconstruction does not affect the timing of chemotherapy. Expand
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Large clinical studies, based on over 200 000 person-years of follow-up, suggest no evidence of an increased risk of lymphoma among women who have received breast implants. Expand
[Antibiotic prophylaxis in breast surgery. Preliminary resuls of a multicenter randomized study on 1400 cases].
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The relationship of nonsteroidal anti-inflammatory drug use to the risk of breast cancer.
The data are compatible with a small reduction in risk associated with regular NSAID use, however, inconsistencies in the data detract from a causal interpretation. Expand