Breast-gut connection: origin of chenodeoxycholic acid in breast cyst fluid

@article{Javitt1994BreastgutCO,
  title={Breast-gut connection: origin of chenodeoxycholic acid in breast cyst fluid},
  author={N. Javitt and K. Budai and U. Raju and M. Levitz and D. Miller and A. Cahan},
  journal={The Lancet},
  year={1994},
  volume={343},
  pages={633-635}
}
The notion that a breast-gut connection might modulate the microenvironment of breast tissue was supported by the finding that breast cyst fluid contains bile acids that are characteristically found in the intestines. To establish that the gut, rather than circulating steroid precursors, is the source of bile acids in breast cyst fluid, we gave two patients deuterium-labelled chenodeoxycholic acid (three 200 mg doses by mouth), starting 9 days before aspiration of breast cysts. The… Expand
Plasma deoxycholic acid concentration is elevated in postmenopausal women with newly diagnosed breast cancer
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