Breast conservation: predictors and treatment of local recurrence.

  title={Breast conservation: predictors and treatment of local recurrence.},
  author={Kevin P. Bethke},
  journal={Seminars in surgical oncology},
  volume={12 5},
Breast conservation therapy has become the preferred treatment for many Stage I and II breast cancers as the "Halstedian" theory of sequential spread has been replaced by the belief that breast cancer is a systemic disease and that local-regional therapy has little impact on overall survival. Local recurrence after conservation therapy is reportedly dependent upon a number of pathological, clinical, and treatment factors. This review examines the complex relationships among these factors, their… CONTINUE READING