Breast cancer stem cells: we've got them surrounded.

@article{Korkaya2013BreastCS,
  title={Breast cancer stem cells: we've got them surrounded.},
  author={Hasan Korkaya and Max S. Wicha},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2013},
  volume={19 3},
  pages={
          511-3
        }
}
Breast cancer stem cells are regulated by cell intrinsic pathways as well as by elements in the tumor microenvironment. New evidence suggests that an important interaction between the interleukin (IL)-8 receptor CXCR1/2 and HER2 is involved in this regulation. Simultaneous targeting of these pathways provides a novel therapeutic approach. 
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CXCR1blockade selectively targets humanbreast cancer stemcells in vitro and in xenografts

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