Breast-cancer risk in families with mutations in PALB2.

  title={Breast-cancer risk in families with mutations in PALB2.},
  author={Victoria Sopik and Steven A Narod},
  journal={The New England journal of medicine},
  volume={371 17},
To the Editor: We read the article by Antoniou et al. (August 7 issue)1 because we like to know the penetrance of breast-cancer genes before we recommend surgery. After reading the article, we are unsure of what to tell patients. The simplest message would be that the risk up to 70 years of age is 35%, but this is based on an analysis of patients who… CONTINUE READING