Breast cancer risk for Korean women with germline mutations in BRCA1 and BRCA2

  title={Breast cancer risk for Korean women with germline mutations in BRCA1 and BRCA2},
  author={Boyoung Park and James G. Dowty and Choonghyun Ahn and Aung Ko Win and Sung-won Kim and Min Hyuk Lee and Jong Won Lee and Eunyoung Kang and John L. Hopper and Sue Kyung Park},
  journal={Breast Cancer Research and Treatment},
The average age-specific cumulative risk (penetrance) of breast cancer has been studied for BRCA1 and BRCA2 mutation carriers living in Western countries, but not for those living in East Asian countries where the population breast cancer incidence is lower. From 2007 to 2011, the Korean Hereditary Breast Cancer study identified 151 BRCA1 and 225 BRCA2 mutation-carrying families from family cancer clinics. We estimated the hazard ratio (HR) for female carriers relative to the population, and… CONTINUE READING
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