Breast cancer incidence in women with a history of progesterone deficiency.

  title={Breast cancer incidence in women with a history of progesterone deficiency.},
  author={Linda Demetry Cowan and Leon Gordis and J A Tonascia and Georgeanna Seegar Jones},
  journal={American journal of epidemiology},
  volume={114 2},
In order to investigate the nature of the association of involuntarily delayed first birth and risk of breast cancer, 1083 white women who had been evaluated and treated for infertility from 1945-1965 were followed prospectively through April 1978 to ascertain their breast cancer incidence. These women were categorized as to the cause of infertility into two groups, those with endogenous progesterone deficiency (PD) and those with nonhormonal causes (NH). Women in the PD group had 5.4 times the… CONTINUE READING
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