Breast cancer: Breast cancer classification

  title={Breast cancer: Breast cancer classification},
  author={Gemma K. Alderton},
  journal={Nature Reviews Cancer},
The alternative lengthening of telomeres (ALT) pathway is a mechanism of maintaining telomere length and is activated in 10–15% of cancers. However, the mechanism of ALT activation is poorly understood. O’Sullivan and colleagues show that knockdown of both ASF1A and ASF1B (histone chaperones that are involved in histone management) in several human cell… CONTINUE READING