Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment

Abstract

Rapidly growing tumours in vivo often outgrow their surrounding available blood supply, subjecting themselves to a severely hypoxic microenvironment. Understanding how tumour cells adapt themselves to survive hypoxia may help to develop new treatments of the tumours. Given the limited blood perfusion to the enlarging tumour, whatever factor(s) that allows… (More)
DOI: 10.1038/srep20605

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@inproceedings{Dong2016BreastCM, title={Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment}, author={Hangming Dong and Mengchen Zou and Ayesha Bhatia and Priyamvada Jayaprakash and Florence M. Hofman and Qilong Ying and Mei Chen and David T. Woodley and Wei Li}, booktitle={Scientific reports}, year={2016} }