Breast Cancer Index predicts pathological complete response and eligibility for breast conserving surgery in breast cancer patients treated with neoadjuvant chemotherapy.

@article{Mathieu2012BreastCI,
  title={Breast Cancer Index predicts pathological complete response and eligibility for breast conserving surgery in breast cancer patients treated with neoadjuvant chemotherapy.},
  author={Marie Christine Mathieu and Chafika Mazouni and Nicole C. Kesty and Yiping Zhang and V{\'e}ronique Scott and J P Passeron and M{\'o}nica Arnedos and Catherine A. Schnabel and Suzette Delaloge and Mark G. Erlander and Fabrice Andr{\'e}},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2012},
  volume={23 8},
  pages={2046-52}
}
BACKGROUND The aim of neoadjuvant chemotherapy is to increase the likelihood of successful breast conservation surgery (BCS). Accurate identification of BCS candidates is a diagnostic challenge. Breast Cancer Index (BCI) predicts recurrence risk in estrogen receptor+lymph node-breast cancer. Performance of BCI to predict chemosensitivity based on pathological complete response (pCR) and BCS was assessed. METHODS Real-time RT-PCR BCI assay was conducted using tumor samples from 150 breast… CONTINUE READING