Breakpoints: current practice and future perspectives.

  title={Breakpoints: current practice and future perspectives.},
  author={Johan W Mouton},
  journal={International journal of antimicrobial agents},
  volume={19 4},
  • Johan W Mouton
  • Published 2002 in International journal of antimicrobial agents
Much of the discussion over the past decades on the value and setting of breakpoints has been due to the fact that the breakpoint was used in two ways; as an indicator to predict the probability of clinical success and also to detect resistant (sub) populations. It is apparent that these two meanings have lead to a different approach to setting, interpretation and use of breakpoints based on clinical efficacy on the one hand and breakpoints based on detection of resistance on the other… CONTINUE READING

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