Breaking through the acid barrier: an orchestrated response to proton stress by enteric bacteria.

@article{Audia2001BreakingTT,
  title={Breaking through the acid barrier: an orchestrated response to proton stress by enteric bacteria.},
  author={Jonathon P. Audia and Cathy C. Webb and John W. Foster},
  journal={International journal of medical microbiology : IJMM},
  year={2001},
  volume={291 2},
  pages={97-106}
}
The ability of enteropathogens such as Salmonella and Escherichia coli to adapt and survive acid stress is fundamental to their pathogenesis. Once inside the host, these organisms encounter life-threatening levels of inorganic acid (H+) in the stomach and a combination of inorganic and organic acids (volatile fatty acids) in the small intestine. To combat these stresses, enteric bacteria have evolved elegant, overlapping strategies that involve both constitutive and inducible defense systems… CONTINUE READING
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