Breaking down the blood-brain barrier: signaling a path to cerebral malaria?

@article{Adams2002BreakingDT,
  title={Breaking down the blood-brain barrier: signaling a path to cerebral malaria?},
  author={Sue Y. Adams and Heidi Brown and Gareth Turner},
  journal={Trends in parasitology},
  year={2002},
  volume={18 8},
  pages={
          360-6
        }
}
  • Sue Y. Adams, Heidi Brown, Gareth Turner
  • Published in Trends in parasitology 2002
  • Biology, Medicine
  • Cerebral malaria is a major killer in the developing world, but we still know very little about the causes of this disease. How does Plasmodium falciparum cause such a devastating neurological disease while it is in the brain vasculature? Why do some patients die, whereas others survive? What processes contribute to disease in the brain, and can we reverse them? Here, the latest evidence from post-mortem, in vitro and animal studies is reviewed to highlight the role of blood-brain barrier… CONTINUE READING

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