Breakdown of HeLa cell DNA mediated by vaccinia virus.

@article{Parkhurst1973BreakdownOH,
  title={Breakdown of HeLa cell DNA mediated by vaccinia virus.},
  author={J R Parkhurst and Andrew R. Peterson and Charles Heidelberger},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1973},
  volume={70 11},
  pages={3200-4}
}
Breakdown of HeLa cell DNA begins within 90 min after infection with vaccinia virus at a multiplicity of infection of 2-plaque-forming units per cell, and ends about 7.5 hr after infection. HeLa cell DNA is degraded to a uniform size of 1 to 2 x 10(7) daltons, as judged by alkaline sucrose sedimentation analysis. The rate of host-cell DNA degradation by… CONTINUE READING