• DOI:10.1126/SCIENCE.1117256
Corpus ID: 38498750

Breakdown of Cortical Effective Connectivity During Sleep

@article{Massimini2005BreakdownOC,
  title={Breakdown of Cortical Effective Connectivity During Sleep},
  author={M. Massimini and F. Ferrarelli and R. Huber and S. Esser and Harpreet Singh and G. Tononi},
  journal={Science},
  year={2005},
  volume={309},
  pages={2228 - 2232}
}

• M. Massimini, F. Ferrarelli, +3 authors G. Tononi
• Published 2005
• Psychology, Medicine
• Science

When we fall asleep, consciousness fades yet the brain remains active. Why is this so? To investigate whether changes in cortical information transmission play a role, we used transcranial magnetic stimulation together with high-density electroencephalography and asked how the activation of one cortical area (the premotor area) is transmitted to the rest of the brain. During quiet wakefulness, an initial response (∼15 milliseconds) at the stimulation site was followed by a sequence of waves… Expand