Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression.

@article{Piantadosi2009BreadthON,
  title={Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression.},
  author={Anne Piantadosi and Dana DeVange Panteleeff and Catherine A. Blish and Jared M Baeten and Walter G. Jaoko and R Scott McClelland and Julie Overbaugh},
  journal={Journal of virology},
  year={2009},
  volume={83 19},
  pages={
          10269-74
        }
}
The determinants of a broad neutralizing antibody (NAb) response and its effect on human immunodeficiency virus type 1 (HIV-1) disease progression are not well defined, partly because most prior studies of a broad NAb response were cross-sectional. We examined correlates of NAb response breadth among 70 HIV-infected, antiretroviral-naïve Kenyan women from a longitudinal seroincident cohort. NAb response breadth was measured 5 years after infection against five subtype A viruses and one subtype… CONTINUE READING

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