Branching of active dendritic spines as a mechanism for controlling synaptic efficacy.

@article{Rusakov1996BranchingOA,
  title={Branching of active dendritic spines as a mechanism for controlling synaptic efficacy.},
  author={Dmitri A. Rusakov and Michael G. Stewart and Sergiy M. Korogod},
  journal={Neuroscience},
  year={1996},
  volume={75 1},
  pages={315-23}
}
Recent experimental findings (Yuste R. and Denk W. (1995) Nature 375, 682-684) suggest that dendritic spines possess excitable membranes. Theoretically, it was shown earlier that the shape of active spines can significantly affect somatopetal synaptic signal transfer. Studies of long-term potentiation in the hippocampus have related the increased synaptic efficacy to a number of structural modifications of spines, including an increased number of branched spines [Trommald M. et al. (1990) In… CONTINUE READING
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