Branchial HOX gene expression and human craniofacial development.

@article{VieilleGrosjean1997BranchialHG,
  title={Branchial HOX gene expression and human craniofacial development.},
  author={I Vieille-Grosjean and Paul N. Hunt and Massimo Gulisano and E. Boncinelli and Peter Thorogood},
  journal={Developmental biology},
  year={1997},
  volume={183 1},
  pages={
          49-60
        }
}
Members of the Antennapedia class of homeobox genes, known as Hox genes, are believed to be pivotal in vertebrate craniofacial development. Here we show that eight members of paralogous groups 1, 2, 3, and 4 are expressed in the human embryonic hindbrain and branchial arches at 4 weeks of development. The combinatorial patterns of expression of genes representing the first three paralogous groups parallel the patterns described for their homologues in various animal models, demonstrating a high… CONTINUE READING
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