Branched-chain amino acids as a protein- and energy-source in liver cirrhosis.

  title={Branched-chain amino acids as a protein- and energy-source in liver cirrhosis.},
  author={Hisataka Moriwaki and Yoshiyuki Miwa and Masahiro Tajika and Masahiko Kato and Hideki Fukushima and Makoto Shiraki},
  journal={Biochemical and biophysical research communications},
  volume={313 2},
Protein-energy malnutrition (PEM) is a common manifestation in cirrhotic patients with reported incidences as high as 65-90%. PEM affects largely the patients' quality of life and survival. Thus, diagnosis of and intervention for PEM is important in the clinical management of liver cirrhosis. Supplementation with branched-chain amino acids (BCAA) is indicated to improve protein malnutrition. As an intervention for energy malnutrition, frequent meal or late evening snack has been recently… CONTINUE READING

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