Branched-chain amino acid interactions in skeletal muscle: isoleucine and L-alloisoleucine.

@article{Downey1986BranchedchainAA,
  title={Branched-chain amino acid interactions in skeletal muscle: isoleucine and L-alloisoleucine.},
  author={Richard S. Downey and Irene E. Karl and Dennis Bier},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={1986},
  volume={10 5},
  pages={
          456-62
        }
}
  • R. Downey, I. Karl, D. Bier
  • Published 1 September 1986
  • Chemistry, Medicine
  • JPEN. Journal of parenteral and enteral nutrition
Parenteral administration of a mixture of branched-chain amino acid (BCAA) solutions is known to alter plasma levels of the BCAA (ILE, LEU, VAL), their corresponding alpha-ketoacids (KMV, KIC, KIV) and L-alloisoleucine (ALLO), a stereoisomer of ILE. Although variously formulated mixtures of BCAA are administered, the metabolic implications of individual BCAA interactions have been only partially elucidated. Using the incubated, isolated, and intact rat epitrochlearis muscle, we measured the… Expand
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