Branched-chain amino acid catabolism and cancer cachexia (review).

The present study focuses on the role of branched-chain amino acids (BCAA) (leucine, isoleucine and valine) in cancer cachexia. This is a frequent and devastating complication of cancer occurring in more than two thirds of patients who die with advanced cancer, and in up to 22% of cancer deaths it is the only abnormality found at autopsy. BCAA are essential… CONTINUE READING