Branched-Chain Amino Acids in Exercise Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise 1 , 2

@inproceedings{Norton2005BranchedChainAA,
  title={Branched-Chain Amino Acids in Exercise Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise 1 , 2},
  author={Layne E. Norton and Donald K Layman},
  year={2005}
}
High-performance physical activity and postexercise recovery lead to significant changes in amino acid and protein metabolism in skeletal muscle. Central to these changes is an increase in the metabolism of the BCAA leucine. During exercise, muscle protein synthesis decreases together with a net increase in protein degradation and stimulation of BCAA oxidation. The decrease in protein synthesis is associated with inhibition of translation initiation factors 4E and 4G and ribosomal protein S6… CONTINUE READING
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