Bran and irritable bowel syndrome: time for reappraisal

@article{Francis1994BranAI,
  title={Bran and irritable bowel syndrome: time for reappraisal},
  author={C. Francis and P. Whorwell},
  journal={The Lancet},
  year={1994},
  volume={344},
  pages={39-40}
}
Whilst following up large numbers of patients with irritable bowel syndrome we got the impression that wholemeal wheat and bran products made people with the condition worse rather than better. [...] Key Method One hundred consecutive new referrals, all of whom had tried bran, were questioned to resolve this issue. 55% of patients were made worse by bran whereas only 10% had found it helpful. With the exception of fruit, other forms of dietary fibre were not as detrimental and proprietary supplements were found…Expand

Paper Mentions

Interventional Clinical Trial
Despite there being no clearcut advantages, one of the most common recommendations in IBS management is to increase the amount of dietary fibres. In some IBS patients fibres have a… Expand
ConditionsIrritable Bowel Syndrome
InterventionDrug
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TLDR
It is probably best to recommend that patients with IBS be left to judge for themselves whether bran helps or exacerbates their symptoms, but there is enough evidence to suggest that the current dogma of routinely treating all IBS sufferers with bran should be challenged. Expand
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Bran and irritable bowel syndrome: the primary-care perspective.
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  • 2006
TLDR
Although not especially effective in primary-care irritable bowel syndrome patients, bran does not cause so many problems and is more helpful than in secondary-care. Expand
87 – Irritable Bowel Syndrome
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Careful pathophysiological and treatment studies, especially in primary care patients and in nonpatients in the community, are needed to help identify the most appropriate management of irritable bowel syndrome. Expand
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There is some preliminary evidence to suggest that elimination diets based on immunoglobulin G food antibody testing may possibly have therapeutic potential in IBS, but this requires confirmation. Expand
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Novel approaches include alosetron; a 5-HT(3) antagonist, tegaserod, a partial 5- HT(4) agonist, kappa-opioid agonists, and neurokinin antagonists to address the remaining challenging symptoms of pain, constipation, and bloating. Expand
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This chapter proposes a management strategy based on a firm diagnosis of IBS using a minimum of tests, consideration of the patient's agenda, the use of dietary advice, the strategic use of drugs only in resistant cases, a graded therapeutic response and continuing care. Expand
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BRAN AND THE IRRITABLE BOWEL