Brainstem motor loops in the control of movement.

  title={Brainstem motor loops in the control of movement.},
  author={Dipankar Nandi and Tipu Z. Aziz and Xuguang Liu and John F. Stein},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={17 Suppl 3},
In recent years, the role of the area around the upper brainstem, particularly the pedunculopontine (PPN) region and the zona incerta (ZI), in the initiation and control of movement has generated much clinical interest. Using electrophysiological and pharmacological methods, we have further explored these structures and their influence in motor control in the nonhuman primate and in patients with proximal tremor. We have found that lesioning the PPN and electrical stimulation at high… CONTINUE READING
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