Brainstem changes in 5-HT1A receptor availability during migraine attack.

  title={Brainstem changes in 5-HT1A receptor availability during migraine attack.},
  author={Genevi{\`e}ve Demarquay and Am{\'e}lie Lothe and J. P. Royet and Nicolas Costes and G{\'e}rard Mick and François Maugui{\`e}re and Philippe Ryvlin},
  journal={Cephalalgia : an international journal of headache},
  volume={31 1},
BACKGROUND Among serotonin receptors, 5-HT(1A) receptors are implicated in the regulation of central serotoninergic tone and could be involved in the abnormal brain 5-HT turnover suspected in migraineurs. The aim of this study was to investigate 5-HT(1A) receptors' availability during migraine attacks. METHODS Ten patients suffering from odor-triggered migraine attacks and 10 control subjects were investigated using positron emission tomography (PET) and [(18)F]MPPF PET tracer, a selective 5… CONTINUE READING
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