BrainAGE in Mild Cognitive Impaired Patients: Predicting the Conversion to Alzheimer’s Disease

@inproceedings{Gaser2013BrainAGEIM,
  title={BrainAGE in Mild Cognitive Impaired Patients: Predicting the Conversion to Alzheimer’s Disease},
  author={Christian Gaser and Katja Franke and Stefan Kl{\"o}ppel and Nikolaos Koutsouleris and Heinrich Sauer},
  booktitle={PloS one},
  year={2013}
}
Alzheimer's disease (AD), the most common form of dementia, shares many aspects of abnormal brain aging. We present a novel magnetic resonance imaging (MRI)-based biomarker that predicts the individual progression of mild cognitive impairment (MCI) to AD on the basis of pathological brain aging patterns. By employing kernel regression methods, the expression of normal brain-aging patterns forms the basis to estimate the brain age of a given new subject. If the estimated age is higher than the… CONTINUE READING