Brain white matter abnormalities in paediatric Gaucher Type I and Type III using diffusion tensor imaging

@article{Davies2011BrainWM,
  title={Brain white matter abnormalities in paediatric Gaucher Type I and Type III using diffusion tensor imaging},
  author={Elin Haf Davies and Kiran K. Seunarine and Tina Banks and Chris A Clark and Ashok Vellodi},
  journal={Journal of Inherited Metabolic Disease},
  year={2011},
  volume={34},
  pages={549-553}
}
Biomarkers to monitor neurological dysfunction in Neuronopathic Gaucher disease (NGD) are lacking. Diffusion tensor imaging (DTI) is a technique which allows us to probe the microstructure of the white-matter of the brain, in-vivo. The aim of this study was to investigate the value of DTI to visualise and quantify white matter integrity in children with NGD… CONTINUE READING