Brain water measured by magnetic resonance imaging. Correlation with direct estimation and changes after mannitol and dexamethasone.

@article{Bell1987BrainWM,
  title={Brain water measured by magnetic resonance imaging. Correlation with direct estimation and changes after mannitol and dexamethasone.},
  author={Barry A. Bell and Mike A. Smith and David Kean and C N McGhee and H L MacDonald and J. Douglas Miller and Gene H. Barnett and J. L. Tocher and Ronald H. Douglas and Jonathan J K Best},
  journal={Lancet},
  year={1987},
  volume={1 8524},
  pages={66-9}
}
Brain water content was measured in tissue samples taken at operation from 19 patients with intrinsic cerebral tumours imaged preoperatively by magnetic resonance. A high correlation (r = 0.94, p less than 0.0001) between white matter water content and the longitudinal relaxation time (T1) enabled water content to be estimated from T1 to within 4%. 11 patients received dexamethasone and improved clinically but their T1, and thus brain water content, was unchanged an average of 6 days later… CONTINUE READING

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