Brain volume changes in the first year of illness and 5-year outcome of schizophrenia.

@article{Cahn2006BrainVC,
  title={Brain volume changes in the first year of illness and 5-year outcome of schizophrenia.},
  author={Wiepke Cahn and Neeltje E.M . van Haren and Hilleke E. Hulshoff Pol and Hugo G. Schnack and Esther Caspers and D A J Laponder and Ren{\'e} S. Kahn},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2006},
  volume={189},
  pages={
          381-2
        }
}
Progressive brain volume changes have been reported in first-episode schizophrenia, but their relationship to the disease process or to other factors remains unclear. We examined such changes in the first year of illness, and related them to 5-year outcome. Progressive brain volume changes, in particular of grey matter, during the first year of illness were found to be significantly associated with clinical and functional outcome 5 years after the first episode. These findings suggest that… CONTINUE READING

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