Brain uptake of the drug of abuse γ-hydroxybutyric acid in rats.

Abstract

γ-Hydroxybutyric acid (GHB) is an endogenous compound and a substrate for the ubiquitous monocarboxylate transporter (MCT) family. GHB is also a drug of abuse due to its sedative/hypnotic and euphoric effects, with overdoses resulting in toxicity and death. The goal of this study was to characterize the distribution of GHB into the brain using in vivo… (More)
DOI: 10.1124/dmd.111.041749

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@article{Roiko2012BrainUO, title={Brain uptake of the drug of abuse γ-hydroxybutyric acid in rats.}, author={Samuel A. Roiko and Melanie A. Felmlee and Marilyn E Morris}, journal={Drug metabolism and disposition: the biological fate of chemicals}, year={2012}, volume={40 1}, pages={212-8} }