Brain tumors and anorexia nervosa syndrome

@article{Chipkevitch1994BrainTA,
  title={Brain tumors and anorexia nervosa syndrome},
  author={Eug{\^e}nio Chipkevitch},
  journal={Brain and Development},
  year={1994},
  volume={16},
  pages={175-179}
}
  • E. Chipkevitch
  • Published 1 May 1994
  • Psychology, Medicine
  • Brain and Development
This review presents 21 cases, found in the literature, of a CNS lesion (a tumor in 19 of them) associated with emaciation, anorexia and several psychic symptoms that had led to the diagnosis of anorexia nervosa (AN). Anorexia and psychic disturbances preceded the neurologic signs and/or the correct diagnosis in all patients (by a mean of 2.9 years, range = 0.2-17 years). Anorexia had begun before the age of 25 years in 18 patients of which two-thirds were females. Only a few cases fulfilled… 
Anorexia Nervosa and Brain Tumor in a 14-Year-Old Girl
TLDR
A 14-year-old girl with anorexia nervosa (AN) was found to have an intracranial neoplasm and appears to be two unrelated conditions, which remain unclear how each affected the other.
Brain tumors and anorexia nervosa syndrome Commentary to Chipkevitch's paper (pp. 175–9)
The interesting paper by Chipkevitch [1] nicely reviews the association of anorexia and brain tumors, and putatively identifies the pathophysiologic correlates of anorexia nervosa. The author rightly
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TLDR
Organic disorder should always be considered before making a diagnosis of anorexia nervosa, particularly if the presentation is atypical.
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TLDR
Right frontal intracerebral lesions with their close relationship to the limbic system could be causative for eating disorders, especially if they occur in combination with focal seizures and performing a cranial MRI in all patients with suspected eating disorders is recommended.
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TLDR
Aversion to food, which especially in young females may frequently have a psychological origin, was the common presenting clinical feature in the current study on two VHL patients with such lesions but no hydrocephalus.
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In addition to careful physical examination, additional neuroimaging is advised especially in each case of atypical presentation of anorexia nervosa, in order to avoid a delay in diagnosis of a possible malignancy.
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TLDR
A 13-year-old girl with coincidental occult intracranial tumor and early-onset anorexia nervosa and the cerebral meningioma was discovered fortuitously as the result of a research project using SPECT imaging to locate a neurobiological substrate in patients with anoremia nervosa.
Slow-growing craniopharyngioma masquarading as early-onset eating disorder: two cases.
TLDR
The reported cases illustrate the importance to consider slow-growing craniopharyngioma in ED, and the possibility of an as yet unidentified structural hypothalamic disorder to be implicated in the etiopathogeny of ED.
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