Brain tumors across the age spectrum: biology, therapy, and late effects.

@article{Merchant2010BrainTA,
  title={Brain tumors across the age spectrum: biology, therapy, and late effects.},
  author={Thomas E. Merchant and Ian F Pollack and Jay Steven Loeffler},
  journal={Seminars in radiation oncology},
  year={2010},
  volume={20 1},
  pages={58-66}
}
The clinical difference between brain tumors in adults and children is striking. Compared with adults, pediatric tumor types (mostly glial and neuronal) are more sensitive to adjuvant irradiation and chemotherapy. Pediatric tumors more often require craniospinal irradiation based on their propensity to disseminate within the neuraxis. The spectrum of side… CONTINUE READING