Brain tumor stem cells.

  title={Brain tumor stem cells.},
  author={Georgia Panagiotakos and Viviane S Tabar},
  journal={Current neurology and neuroscience reports},
  volume={7 3},
The concept of brain tumor stem cells is gaining increased recognition in neuro-oncology. Until recently, the paradigm of a tumor-initiating stem cell was confined to hematopoietic malignancies where the hierarchical lineages of stem progenitor cells are well established. The demonstration of persistent stem cells and cycling progenitors in the adult brain, coupled with the expansion of the cancer stem cell concept to solid tumors, has led to the exploration of "stemness" within gliomas… CONTINUE READING