Brain tumor-polyposis syndrome: two genetic diseases?

@article{Paraf1997BrainTS,
  title={Brain tumor-polyposis syndrome: two genetic diseases?},
  author={François Paraf and Serge Jothy and Erwin G. Van Meir},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1997},
  volume={15 7},
  pages={
          2744-58
        }
}
PURPOSE AND DESIGN This report presents a comprehensive and statistical analysis of the brain tumor-polyposis (BTP) cases referred to as Turcot's syndrome in the literature. RESULTS BTP patients encompass a heterogeneous group that can be classified into two statistically distinct clinical entities based on phenotype of the polyps (P = .0001), presence of colorectal cancer (P = .0001), type of brain neoplasm, ie, glioma or medulloblastoma (P = .0001), presence of skin lesions (P = .0004) and… CONTINUE READING

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