Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.

@article{Kalsotra2006BrainTL,
  title={Brain trauma leads to enhanced lung inflammation and injury: evidence for role of P4504Fs in resolution.},
  author={Auinash Kalsotra and Junhui Zhao and Sayeepriyadarshini Anakk and Pramod K Dash and Henry W. Strobel},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2006},
  volume={27 5},
  pages={
          963-74
        }
}
Traumatic brain injury is known to cause several secondary effects, which lead to multiple organ dysfunction syndrome. An acute systemic inflammatory response seems to play an integral role in the development of such complications providing the potential for massive secondary injury. We show that a contusion injury to the rat brain causes large migration of inflammatory cells (especially macrophages and neutrophils) in the major airways and alveolar spaces at 24 h post-injury, which is… CONTINUE READING
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