Brain tissue oxygen response in severe traumatic brain injury

  title={Brain tissue oxygen response in severe traumatic brain injury},
  author={Henk van Santbrink and Willie Brink and Ewout Willem Steyerberg and J. A. Carmona Suazo and Cees J. J. Avezaat and Andrew I. R. Maas},
  journal={Acta Neurochirurgica},
¶Objective. To investigate clinical relevance and prognostic value of brain tissue oxygen response (TOR: response of brain tissue pO2 to changes in arterial pO2) in traumatic brain injury (TBI). Patients and methods. In a prospective cohort study TOR was investigated in 41 patients with severe TBI (Glasgow Coma Score ≤8) in whom continuous monitoring of brain tissue oxygen pressure (PbrO2) was performed. TOR was investigated each day over a five day period for 15 minutes by increasing FiO2 on… CONTINUE READING


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