Brain tissue oxygen consumption and supply induced by neural activation: determined under suppressed hemodynamic response conditions in the anesthetized rat cerebral cortex.

The dynamic changes in cerebral metabolic rate of oxygen (CMRO2) and oxygen supply during brain functions have not been well-characterized. To examine this issue, experiments with electrophysiology, oxygen microelectrode and laser-Doppler flowmetry were performed in the anesthetized rat somatosensory cortex. During neural activation, brain tissue partial… CONTINUE READING