Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E

Abstract

BACKGROUND The present study takes advantage of the beneficial effects of resveratrol as a neuroprotective compound. Resveratrol-loaded solid lipid nanoparticles were functionalized with apolipoprotein E which can be recognized by the LDL receptors overexpressed on the blood-brain barrier. RESULTS Transmission electron microscopy images revealed spherical… (More)
DOI: 10.1186/s12951-016-0177-x

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