Brain structure and symptom dimension relationships in obsessive-compulsive disorder: a voxel-based morphometry study.

@article{Gilbert2008BrainSA,
  title={Brain structure and symptom dimension relationships in obsessive-compulsive disorder: a voxel-based morphometry study.},
  author={Andrew R Gilbert and D Mataix-Cols and Jorge Renner Cardoso de Almeida and Natalia L Lawrence and Jeffrey J Nutche and Vaibhav A. Diwadkar and Matcheri S. Keshavan and Mary L. Phillips},
  journal={Journal of affective disorders},
  year={2008},
  volume={109 1-2},
  pages={117-26}
}
BACKGROUND Obsessive-compulsive disorder (OCD) is a clinically heterogenous disorder characterized by temporally stable symptom dimensions. Past inconsistent results from structural neuroimaging studies of OCD may have resulted from the effects of these specific symptom dimensions as well as other socio-demographic and clinical variables upon gray matter (GM) volume. METHODS GM volume was measured in 25 adult OCD patients and 20 adult healthy controls using voxel-based morphometry (VBM… CONTINUE READING