Brain structure and function related to cognitive reserve variables in normal aging, mild cognitive impairment and Alzheimer's disease.

Abstract

Cognitive reserve (CR) is the brain's capacity to cope with cerebral damage to minimize clinical manifestations. The 'passive model' considers head or brain measures as anatomical substrates of CR, whereas the 'active model' emphasizes the use of brain networks effectively. Sixteen healthy subjects, 12 amnestic mild cognitive impairment (MCI) and 16 cases… (More)

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Cite this paper

@article{SolPadulls2009BrainSA, title={Brain structure and function related to cognitive reserve variables in normal aging, mild cognitive impairment and Alzheimer's disease.}, author={Cristina Sol{\'e}-Padull{\'e}s and David Bartr{\'e}s-Faz and Carme Junque and Pere Vendrell and Lorena Rami and Imma C. Clemente and Beatriu Bosch and Amparo Villar and N{\'u}ria Bargall{\'o} and M. A. Jurado and Maite Barrios and Jos{\'e} Luis Molinuevo}, journal={Neurobiology of aging}, year={2009}, volume={30 7}, pages={1114-24} }