Brain structural trajectories over the adult lifespan.

  title={Brain structural trajectories over the adult lifespan.},
  author={Gabriel Ziegler and Robert Dahnke and Lutz J{\"a}ncke and Rachel Aine Yotter and Arne May and Christian Gaser},
  journal={Human brain mapping},
  volume={33 10},
The aim of this large-sample cross-sectional voxel-based morphometry (VBM) study of anatomical brain data was to investigate linear and nonlinear age-related trajectories of grey matter volume in the human brain during the adult lifespan. To date, there are only a few structural brain studies investigating local nonlinear aspects at the voxel level, i.e., without using anatomical ROIs as a priori hypothesis. Therefore, we analyzed 547 T1-weighted MR images of healthy adult brains with an age… CONTINUE READING
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