Brain structural complexity and life course cognitive change

  title={Brain structural complexity and life course cognitive change},
  author={Nazahah Mustafa and Trevor S. Ahearn and Gordon D. Waiter and Alison D. Murray and Lawrence J. Whalley and Roger T. Staff},
Fractal measures such as fractal dimension (FD) can quantify the structural complexity of the brain. These have been used in clinical neuroscience to investigate brain development, ageing and in studies of psychiatric and neurological disorders. Here, we examined associations between the FD of white matter and cognitive changes across the life course in the absence of detectable brain disease. The FD was calculated from segmented cerebral white matter MR images in 217 subjects aged about… CONTINUE READING