Brain stem control of arterial pressure in chronic arterial baroreceptor-denervated rats.

@article{Schreihofer2005BrainSC,
  title={Brain stem control of arterial pressure in chronic arterial baroreceptor-denervated rats.},
  author={Ann M Schreihofer and Satoru Ito and Alan F. Sved},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2005},
  volume={289 6},
  pages={R1746-55}
}
Interruption of the baroreceptor reflex by transection of afferent nerves (sinoaortic denervation; SAD) or lesions of nucleus tractus solitarius (NTS) elevates sympathetic nerve activity (SNA) and arterial pressure (AP). However, within 1 wk, mean AP returns to normal despite the absence of baroreflexes. In this study, we examine central mechanisms that control AP in chronic baroreceptor-denervated rats. In urethane-anesthetized rats (1.5 g/kg i.v.) after autonomic ganglionic blockade (5 mg/kg… CONTINUE READING
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