Brain somatic mutations: the dark matter of psychiatric genetics?

Abstract

Although inherited DNA sequences have a well-demonstrated role in psychiatric disease risk, for even the most heritable mental disorders, monozygotic twins are discordant at a significant rate. The genetic variation associated with mental disorders has heretofore been based on the search for rare or common variation in blood cells. This search is based on… (More)
DOI: 10.1038/mp.2013.168

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