Brain serotonin reuptake did not change during one year in overtrained athletes.

@article{Uusitalo2006BrainSR,
  title={Brain serotonin reuptake did not change during one year in overtrained athletes.},
  author={Arja L T Uusitalo and E. Vanninen and Minna Valkonen-Korhonen and Jyrki T. Kuikka},
  journal={International journal of sports medicine},
  year={2006},
  volume={27 9},
  pages={702-8}
}
Brain 5-HT neurotransmission has been described to be down-regulated in depressed people, and also suspected to be changed in overtraining state, the consequence of long-term physical overloading and stress in athletes. We studied brain serotonin (5-HT) transporter binding i.e., 5-HT reuptake with the specific radioligand (123-I-labelled 2beta-carbomethoxy-3beta[4-iodopenyl]-nortropane, Nor-beta-CIT), and with single photon emission tomography (SPET) in severely overtrained athletes and their… CONTINUE READING