Brain serotonin blockade and paradoxical salt intake in rats.

  title={Brain serotonin blockade and paradoxical salt intake in rats.},
  author={Laurival Ant{\^o}nio De Luca and Silas Pereira Barbosa and Jos{\'e} Vanderlei Menani},
  volume={121 4},
Serotonin antagonism in the lateral parabrachial nucleus (LPBN) enhances sodium appetite induced by hypovolaemia and angiotensin-mineralocorticoid activation, but produces no sodium intake in euhydrated animals. In the present work, male adult rats (n=21) that received bilateral injections of the serotonergic antagonist methysergide (4 microg/0.2 microl) into the LPBN combined to intragastric load of 2 M NaCl (2 ml/rat), ingested hypertonic NaCl (ingestion of 4.3 +/- 1.6 ml/2 h of 0.3 M NaCl… CONTINUE READING
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