Brain responses to visceral and somatic stimuli in irritable bowel syndrome: a central nervous system disorder?

@article{Chang2005BrainRT,
  title={Brain responses to visceral and somatic stimuli in irritable bowel syndrome: a central nervous system disorder?},
  author={L Cindy Chang},
  journal={Gastroenterology clinics of North America},
  year={2005},
  volume={34 2},
  pages={271-9}
}
  • L Cindy Chang
  • Published 2005 in Gastroenterology clinics of North America
In healthy subjects, the brain regions most consistently activated in visceral and somatic pain are the key regions in the central pain matrix,including the mid/anterior insula, subregions of the ACC, PFC, thalamus,and in some cases, pontine regions such as the dorsal pons and PAG. Functional neuroimaging studies have demonstrated evidence of altered regional brain activation responses during visceral and somatic stimuli in IBS that have been associated with perceptual differences. Although… CONTINUE READING
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